Avaliação Laboratorial de Anticorpos Contra o Vírus da Hepatite C em Voluntários Imunizados contra a Hepatite B
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Jan 8, 2006
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Abstract
Considerando que (1) após a imunização contra o HBV é possível detectarmos níveis séricos de anti-HBc e anti-HBSag, (2) a infecção pelo HBV ocorre, principalmente, através de contato sexual, sendo mais freqüentemente associada com os vírus das hepatites tipos A, B, C e Delta com evolução para doenças hepática crônica e (3) a definição do agente infeccioso responsável pela hepatite C (diagnóstico etiológico) é dada através da investigação do marcador sorológico Anti-HCV, este trabalho apresentou como objetivo investigar, através de ensaio de ELISA, a possível reação cruzada de anticorpos contra o vírus da Hepatite C em voluntários imunizados contra a Hepatite B. Assim, neste estudo, selecionamos 20 voluntários (ambos os sexos) imunizados contra o vírus da hepatite B e que relataram não serem portadores do vírus da hepatite C. Em amostras de soro, foi realizada, através de ensaio imunoenzimático (ELISA), a pesquisa de anticorpos IgM contra o vírus da hepatite C. A análise laboratorial revelou que todos os voluntários selecionados não foram capazes de produzir anticorpos contra o vírus da hepatite C quando submetidos à imunização contra o vírus da hepatite B. Este estudo mostra que a imunização contra o vírus da hepatite B realizada na Rede Pública de Saúde é, exclusivamente, capaz de produzir resposta imune humoral somente contra este agente viral e não permite a estimulação de anticorpos inespecíficos.
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Santana Garcia, E. C. de, & Joviliano, R. D.-. (2006). Avaliação Laboratorial de Anticorpos Contra o Vírus da Hepatite C em Voluntários Imunizados contra a Hepatite B. Revista Brasileira Multidisciplinar, 10(2), 17-30. https://doi.org/10.25061/2527-2675/ReBraM/2006.v10i2.245
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Authors retain the copyright and grant the journal the right of first publication, with the work simultaneously licensed under the Creative Commons Attribution License, which allows the sharing of work with acknowledgment of authorship and initial publication in this journal.
Authors are authorized to take additional contracts separately, for non-exclusive distribution of the version of the work published in this journal (eg publish in institutional repository or as book chapter), with acknowledgment of authorship and initial publication in this journal.
Authors are allowed and encouraged to publish and distribute their work online (eg in institutional repositories or on their personal page) at any point before or during the editorial process, as this can generate productive changes as well as increase the impact and citation of the published work (See The Effect of Free Access) at http://opcit.eprints.org/oacitation-biblio.html
