Tratamentos naturais para controle da ansiedade: revisão crítica de ensaios clínicos randomizados e quase randomizados
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Abstract
Objective: To evaluate natural treatments incorporated into complementary, alternative and integrative medicine for the control of anxiety disorders (AD) through a critical review of randomized and quasi-randomized clinical trials. Materials and methods: Five electronic databases were used according to the eligibility criteria. After eliminating duplicates and reading titles and abstracts, data were tabulated in Excel® 2016 and VantagePoint™. Descriptive analysis of the variables type of treatment, age group, drug presentation, natural product, efficacy and adverse effects, journal and its impact factor, number of citations in Scopus and Google Scholar databases were performed. Results: Thirty studies were included. The most cited study has 337 citations in Google Scholar and 192 in Scopus. Of the treatments, 28 (93.33%) were herbal medicines, one (3.33%) homeopathic and one (3.33%) flower remedies. Fifteen studies were carried out in adults, 14 in adults and the elderly and one in adolescents. Capsule (n=18), pastille (n=6) and solution (n=1) were the drug presentations, with clinically proven positive effect (n=25; 83%). Nausea, dizziness, headaches and drowsiness have been reported. Piper methysticum, Matricaria recutita, Ginkgo biloba, Passiflora incarnata, Withania somnifera and Centella asiatica were the natural products studied. Conclusion: Natural treatments incorporated into complementary, alternative and integrative medicine for the control of ED have been published in the last 24 years, especially in developed countries and in journals with varied impact factors. Phytotherapy is the most used type of treatment for ED, and its positive effects have been clinically proven.
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