Prevalence of Haemoglobine s in Araraquara-SP Population.
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Published:
Jan 10, 2008
Keywords:
Anemia, Hemoglobin, Sickle Cell, Sickling, Solubility. Anemia, Hemoglobinas, Falciforme, Falcização, Solubilidade
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Abstract
The Sickle Cell Anemia is a genetic hemoglobionopathy, characterized by an alteration in the hemoglobin molecule struture (HbA1), called hemoglobin S (HbS), which causes a distortion in the erythocytes structure, changing from spherical shape to sickle shape (sickle-cell), a sickling phenomenon, which leads to severe anemia in homozygous, while sickle cell trait (heterozygote) leads to pain crisis, according to pathophysiology, in low O2 blood pressure situations. The most specific and sensitive test used to diagnose this anemia is the hemoglobin eletrophoresis test, which is, however, hard to be incorporated in routine laboratories, due to its high cost. The objective of this work was to estimate the sickle cell trait prevalence in Araraquara - SP population. The prevalence of asymptomatic individuals with the sickle cell trait was 1.5%. Considering the study of race prevalence, 0,6% of sickle cell trait in white individuals and 15,4% in black ones were found.
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How to Cite
Jesus, B. R. de, Rin, H. B., Leite, E. R. M., Leite, A. A., & Gileno, M. da C. (2008). Prevalence of Haemoglobine s in Araraquara-SP Population. Revista Brasileira Multidisciplinar, 11(2), 230-237. https://doi.org/10.25061/2527-2675/ReBraM/2007.v11i2.194
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• Publishers have the right to make textual adjustments and to adapt the article to the rules of publication.
Authors retain the copyright and grant the journal the right of first publication, with the work simultaneously licensed under the Creative Commons Attribution License, which allows the sharing of work with acknowledgment of authorship and initial publication in this journal.
Authors are authorized to take additional contracts separately, for non-exclusive distribution of the version of the work published in this journal (eg publish in institutional repository or as book chapter), with acknowledgment of authorship and initial publication in this journal.
Authors are allowed and encouraged to publish and distribute their work online (eg in institutional repositories or on their personal page) at any point before or during the editorial process, as this can generate productive changes as well as increase the impact and citation of the published work (See The Effect of Free Access) at http://opcit.eprints.org/oacitation-biblio.html