The Effects of "Barbatimão" Ointment (Stryphnodendrom Barbatiman Martius) Associated with Low Intensity Ultrasound on the Healing of Total Cutaneous Lesions in Rats
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Abstract
Related researches for the treatment of skin wounds is a matter of interest to researchers seeking new products and technology with the possibility of accelerating the healing process. The present study had as aim to analyze the healing action of "Barbatimão" ointment at 5% (Stryphnodendrom Barbatiman Martius) associated with low intensity pulsed ultrasound on the second intention healing process. The experiment was carried out using 24 Wistar rats (250-300g) divided into 4 groups: A was the control group, B: was treated with Barbatiman ointment, C: with pulsating ultrasound and D: with a combination of pulsating ultrasound and Barbatiman ointment. After anaesthesia with Ketamin 100g/kg and Xilamin chlorohidrate 6mg/kg, the dorsal region of the animal was shaved and an approximate 1.0 cm2 incision into the subcutaneous tissue was made. It was seen that in the first 5 days of treatment (p=0,1) the pulsating Ultrasound presented the best healing when compared to the "Barbatimão" ointment (p=0.2). However, after 10 days the lesions treated with "Barbatimão" showed that this treatment was better (p=0.3) compared to the pulsating ultrasound (p=0.9), but the association of the two types of treatments was not as successful at accelerating the healing process. Thus it was determined that separately they were more efficient at healing wounds.
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Ballaben, A. S., Crisci, A. R., & Jorge, M. H. S. (2013). The Effects of "Barbatimão" Ointment (Stryphnodendrom Barbatiman Martius) Associated with Low Intensity Ultrasound on the Healing of Total Cutaneous Lesions in Rats. Revista Brasileira Multidisciplinar, 16(1), 159-172. https://doi.org/10.25061/2527-2675/ReBraM/2013.v16i1.53
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Artigos Originais
1437/5000
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• The journal is not responsible for the opinions, ideas and concepts issued in the texts, as they are the sole responsibility of the author (s);
• Publishers have the right to make textual adjustments and to adapt the article to the rules of publication.
Authors retain the copyright and grant the journal the right of first publication, with the work simultaneously licensed under the Creative Commons Attribution License, which allows the sharing of work with acknowledgment of authorship and initial publication in this journal.
Authors are authorized to take additional contracts separately, for non-exclusive distribution of the version of the work published in this journal (eg publish in institutional repository or as book chapter), with acknowledgment of authorship and initial publication in this journal.
Authors are allowed and encouraged to publish and distribute their work online (eg in institutional repositories or on their personal page) at any point before or during the editorial process, as this can generate productive changes as well as increase the impact and citation of the published work (See The Effect of Free Access) at http://opcit.eprints.org/oacitation-biblio.html